PDF DatasheetHuman XRP2 / RP2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant XRP2 / RP2 based upon sequence from Human
Host: QP6617 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) XRP2 / RP2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6617.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly1 – Ile350
Amino Acid Sequence: GCFFSKRRKA DKESRPENEE ERPKQYSWDQ REKVDPKDYM FSGLKDETVG RLPGTVAGQQ FLIQDCENCN IYIFDHSATV TIDDCTNCII FLGPVKGSVF FRNCRDCKCT LACQQFRVRD CRKLEVFLCC ATQPIIESSS NIKFGCFQWY YPELAFQFKD AGLSIFNNTW SNIHDFTPVS GELNWSLLPE DAVVQDYVPI PTTEELKAVR VSTEANRSIV PISRGQRQKS SDESCLVVLF AGDYTIANAR KLIDEMVGKG FFLVQTKEVS MKAEDAQRVF REKAPDFLPL LNKGPVIALE FNGDGAVEVC QLIVNEIFNG TKMFVSESKE TASGDVDSFY NFADIQMGI
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human XRP2 / RP2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human XRP2 / RP2 Protein General Information | |
|---|---|
| Alternate Names | |
| XRP2, RP2, TBCCD2, DELXp11.3, NM23-H10, NME10, XRP2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RP2 |
| Entrez Gene ID | 6102 |
| Ensemble Gene ID | ENSG00000102218 |
| RefSeq Protein Accession(s) | NP_008846.2 |
| RefSeq mRNA Accession(s) | NM_006915.2 |
| UniProt ID(s) | O75695 |
| UniGene ID(s) | Hs.44766 |
| HGNC ID(s) | HGNC:10274 |
| COSMIC ID Link(s) | RP2 |
| KEGG Gene ID(s) | hsa:6102 |
| PharmGKB ID(s) | PA34641 |
| General Description of Recombinant Human XRP2 / RP2 Protein. | |
| Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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