PDF DatasheetHuman RRM2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant RRM2 based upon sequence from Human
Host: QP6630 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) RRM2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6630.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Phe38
Amino Acid Sequence: MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS KDIQHWESLK PEERYFISHV LAFFAASDGI VNENLVERFS QEVQITEARC FYGFQIAMEN IHSEMYSLLI DTYIKDPKER EFLFNAIETM PCVKKKADWA LRWIGDKEAT YGERVVAFAA VEGIFFSGSF ASIFWLKKRG LMPGLTFSNE LISRDEGLHC DFACLMFKHL VHKPSEERVR EIIINAVRIE QEFLTEALPV KLIGMNCTLM KQYIEFVADR LMLELGFSKV FRVENPFDFM ENISLEGKTN FFEKRVGEYQ RMGVMSSPTE NSFTLDADF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human RRM2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human RRM2 Protein General Information | |
|---|---|
| Alternate Names | |
| R2, RR2, RR2M, Ribonucleoside-diphosphate reductase subunit | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RRM2 |
| Entrez Gene ID | 6241 |
| Ensemble Gene ID | ENSG00000171848 |
| RefSeq Protein Accession(s) | NP_001025.1 |
| RefSeq mRNA Accession(s) | NM_001034.3, NM_001165931.1 |
| UniProt ID(s) | P31350 |
| UniGene ID(s) | Hs.226390 |
| HGNC ID(s) | HGNC:10452 |
| COSMIC ID Link(s) | RRM2 |
| KEGG Gene ID(s) | hsa:6241 |
| PharmGKB ID(s) | PA299 |
| General Description of Recombinant Human RRM2 Protein. | |
| Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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