PDF DatasheetHuman Runt-related transcription factor 3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Runt-related transcription factor 3 based upon sequence from Human
Host: QP6632 protein expressed in E. coli.
Tag: His-Myc
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Runt-related transcription factor 3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6632.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Tyr415
Amino Acid Sequence: MRIPVDPSTS RRFTPPSPAF PCGGGGGKMG ENSGALSAQA AVGPGGRARP EVRSMVDVLA DHAGELVRTD SPNFLCSVLP SHWRCNKTLP VAFKVVALGD VPDGTVVTVM AGNDENYSAE LRNASAVMKN QVARFNDLRF VGRSGRGKSF TLTITVFTNP TQVATYHRAI KVTVDGPREP RRHRQKLEDQ TKPFPDRFGD LERLRMRVTP STPSPRGSLS TTSHFSSQPQ TPIQGTSELN PFSDPRQFDR SFPTLPTLTE SRFPDPRMHY PGAMSAAFPY SATPSGTSIS SLSVAGMPAT SRFHHTYLPP PYPGAPQNQS GPFQANPSPY HLYYGTSSGS YQFSMVAGSS SGGDRSPTRM LASCTSSAAS VAAGNLMNPS LGGQSDGVEA DGSHSNSPTA LSTPGRMDEA VWRPY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Runt-related transcription factor 3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Runt-related transcription factor 3 Protein General Information | |
|---|---|
| Alternate Names | |
| AML2, CBFA3, PEBP2aC | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RUNX3 |
| Entrez Gene ID | 864 |
| Ensemble Gene ID | ENSG00000020633 |
| RefSeq Protein Accession(s) | NP_001026850.1 |
| RefSeq mRNA Accession(s) | NM_001031680.2, NM_001320672.1, NM_004350.2, XM_005246024.4 |
| UniProt ID(s) | Q13761 |
| UniGene ID(s) | Hs.170019 |
| HGNC ID(s) | HGNC:10473 |
| COSMIC ID Link(s) | RUNX3 |
| KEGG Gene ID(s) | hsa:864 |
| PharmGKB ID(s) | PA34886 |
| General Description of Recombinant Human Runt-related transcription factor 3 Protein. | |
| CBF binds to the core site, 5′-PYGPYGGT-3′, of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters. In association with ZFHX3, upregulates CDKN1A promoter activity following TGF-beta stimulation (PubMed:20599712). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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