PDF DatasheetRat SerpinA1 / A1AT Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant SerpinA1 / A1AT based upon sequence from Rat
Host: QP6666 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) SerpinA1 / A1AT, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6666.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu25 – Arg411
Amino Acid Sequence: EDAQETDTSQ QDQSPTYRKI SSNLADFAFS LYRELVHQSN TSNIFFSPMS ITTAFAMLSL GSKGDTRKQI LEGLEFNLTQ IPEADIHKAF HHLLQTLNRP DSELQLNTGN GLFVNKNLKL VEKFLEEVKN NYHSEAFSVN FADSEEAKKV INDYVEKGTQ GKIVDLMKQL DEDTVFALVN YIFFKGKWKR PFNPEHTRDA DFHVDKSTTV KVPMMNRLGM FDMHYCSTLS SWVLMMDYLG NATAIFLLPD DGKMQHLEQT LTKDLISRFL LNRQTRSAIL YFPKLSISGT YNLKTLLSSL GITRVFNNDA DLSGITEDAP LKLSQAVHKA VLTLDERGTE AAGATVVEAV PMSLPPQVKF DHPFIFMIVE SETQSPLFVG KVIDPTR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Rat SerpinA1 / A1AT Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Rat SerpinA1 / A1AT Protein General Information | |
|---|---|
| Alternate Names | |
| SerpinA1, A1AT, AAT, PRO2275, alpha1AT, A1A, A1AT, PI, PI1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Serpina1 |
| Entrez Gene ID | 24648 |
| RefSeq Protein Accession(s) | NP_071964.2 |
| RefSeq mRNA Accession(s) | NM_022519.2, XM_006240456.1, XM_017594032.1 |
| UniProt ID(s) | P17475 |
| UniGene ID(s) | Rn.1419 |
| COSMIC ID Link(s) | Serpina1 |
| KEGG Gene ID(s) | rno:24648 |
| General Description of Recombinant Rat SerpinA1 / A1AT Protein. | |
| Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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