PDF DatasheetHuman gp100 / PMEL17 / SILV Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant gp100 / PMEL17 / SILV based upon sequence from Human
Host: QP6683 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) gp100 / PMEL17 / SILV, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6683.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Lys25 – Val467
Amino Acid Sequence: KVPRNQDWLG VSRQLRTKAW NRQLYPEWTE AQRLDCWRGG QVSLKVSNDG PTLIGANASF SIALNFPGSQ KVLPDGQVIW VNNTIINGSQ VWGGQPVYPQ ETDDACIFPD GGPCPSGSWS QKRSFVYVWK TWGQYWQVLG GPVSGLSIGT GRAMLGTHTM EVTVYHRRGS RSYVPLAHSS SAFTITDQVP FSVSVSQLRA LDGGNKHFLR NQPLTFALQL HDPSGYLAEA DLSYTWDFGD SSGTLISRAL VVTHTYLEPG PVTAQVVLQA AIPLTSCGSS PVPGTTDGHR PTAEAPNTTA GQVPTTEVVG TTPGQAPTAE PSGTTSVQVP TTEVISTAPV QMPTAESTGM TPEKVPVSEV MGTTLAEMST PEATGMTPAE VSIVVLSGTT AAQVTTTEWV ETTARELPIP EPEGPDASSI MSTESITGSL GPLLDGTATL RLV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human gp100 / PMEL17 / SILV Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human gp100 / PMEL17 / SILV Protein General Information | |
|---|---|
| Alternate Names | |
| gp100, PMEL17, SILV, gp100, PMEL17, SI, D12S53E, P1, ME20-M, P100, SILV, ME20, SIL, ME20M | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SILV |
| Entrez Gene ID | 6490 |
| Ensemble Gene ID | ENSG00000185664 |
| RefSeq Protein Accession(s) | NP_001186982.1 |
| RefSeq mRNA Accession(s) | NM_001200053.1, NM_001200054.1, NM_001320121.1, NM_001320122.1, NM_006928.4, XM_006719569.1, XM_011538685.1 |
| UniProt ID(s) | P40967 |
| UniGene ID(s) | Hs.95972 |
| HGNC ID(s) | HGNC:10880 |
| KEGG Gene ID(s) | hsa:6490 |
| PharmGKB ID(s) | PA35781 |
| General Description of Recombinant Human gp100 / PMEL17 / SILV Protein. | |
| Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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