PDF DatasheetHuman Apoptosis regulatory protein Siva Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Apoptosis regulatory protein Siva based upon sequence from Human
Isoform: Isoform 2
Host: QP6688 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Apoptosis regulatory protein Siva, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6688.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Thr110
Amino Acid Sequence: MPKRSCPFAD VAPLQLKVRV SQRELSRGVC AERYSQEVFD PSGVASIACS SCVRAVDGKA VCGQCERALC GQCVRTCWGC GSVACTLCGL VDCSDMYEKV LCTSCAMFET
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Apoptosis regulatory protein Siva Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Apoptosis regulatory protein Siva Protein General Information | |
|---|---|
| Alternate Names | |
| CD27BP, SIVA, Siva-1, Siva-2 | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SIVA1 |
| Entrez Gene ID | 10572 |
| Ensemble Gene ID | ENSG00000184990 |
| RefSeq Protein Accession(s) | NP_006418.2 |
| RefSeq mRNA Accession(s) | NM_006427.3, NM_021709.2 |
| UniProt ID(s) | O15304 |
| UniGene ID(s) | Hs.112058 |
| HGNC ID(s) | HGNC:17712 |
| COSMIC ID Link(s) | SIVA1 |
| KEGG Gene ID(s) | hsa:10572 |
| PharmGKB ID(s) | PA162403351 |
| General Description of Recombinant Human Apoptosis regulatory protein Siva Protein. | |
| Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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