PDF DatasheetHuman Very long-chain acyl-CoA synthetase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Very long-chain acyl-CoA synthetase based upon sequence from Human
Host: QP6694 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Very long-chain acyl-CoA synthetase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6694.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Gly283 – Leu620
Amino Acid Sequence: GATLALRTKF SASQFWDDCR KYNVTVIQYI GELLRYLCNS PQKPNDRDHK VRLALGNGLR GDVWRQFVKR FGDICIYEFY AATEGNIGFM NYARKVGAVG RVNYLQKKII TYDLIKYDVE KDEPVRDENG YCVRVPKGEV GLLVCKITQL TPFNGYAGAK AQTEKKKLRD VFKKGDLYFN SGDLLMVDHE NFIYFHDRVG DTFRWKGENV ATTEVADTVG LVDFVQEVNV YGVHVPDHEG RIGMASIKMK ENHEFDGKKL FQHIADYLPS YARPRFLRIQ DTIEITGTFK HRKMTLVEEG FNPAVIKDAL YFLDDTAKMY VPMTEDIYNA ISAKTLKL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Very long-chain acyl-CoA synthetase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Very long-chain acyl-CoA synthetase Protein General Information | |
|---|---|
| Alternate Names | |
| FATP2, VLCS, ACSVL1, FACVL1, VLACS, HsT17226, hFACVL1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SLC27A2 |
| Entrez Gene ID | 11001 |
| Ensemble Gene ID | ENSG00000140284 |
| RefSeq Protein Accession(s) | NP_001153101.1 |
| RefSeq mRNA Accession(s) | NM_001159629.1, NM_003645.3 |
| UniProt ID(s) | O14975 |
| UniGene ID(s) | Hs.11729 |
| HGNC ID(s) | HGNC:10996 |
| COSMIC ID Link(s) | SLC27A2 |
| KEGG Gene ID(s) | hsa:11001 |
| PharmGKB ID(s) | PA27971 |
| General Description of Recombinant Human Very long-chain acyl-CoA synthetase Protein. | |
| Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across mbranes . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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