PDF DatasheetHuman Transcription factor SOX-2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Transcription factor SOX-2 based upon sequence from Human
Host: QP6718 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Transcription factor SOX-2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6718.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Met317
Amino Acid Sequence: MYNMMETELK PPGPQQTSGG GGGNSTAAAA GGNQKNSPDR VKRPMNAFMV WSRGQRRKMA QENPKMHNSE ISKRLGAEWK LLSETEKRPF IDEAKRLRAL HMKEHPDYKY RPRRKTKTLM KKDKYTLPGG LLAPGGNSMA SGVGVGAGLG AGVNQRMDSY AHMNGWSNGS YSMMQDQLGY PQHPGLNAHG AAQMQPMHRY DVSALQYNSM TSSQTYMNGS PTYSMSYSQQ GTPGMALGSM GSVVKSEASS SPPVVTSSSH SRAPCQAGDL RDMISMYLPG AEVPEPAAPS RLHMSQHYQS GPVPGTAING TLPLSHM
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Transcription factor SOX-2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Transcription factor SOX-2 Protein General Information | |
|---|---|
| Alternate Names | |
| MCOPS3, ANOP3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SOX2 |
| Entrez Gene ID | 6657 |
| Ensemble Gene ID | ENSG00000181449 |
| RefSeq Protein Accession(s) | NP_003097.1 |
| RefSeq mRNA Accession(s) | NM_003106.3 |
| UniProt ID(s) | P48431 |
| UniGene ID(s) | Hs.518438 |
| HGNC ID(s) | HGNC:11195 |
| COSMIC ID Link(s) | SOX2 |
| KEGG Gene ID(s) | hsa:6657 |
| PharmGKB ID(s) | PA36032 |
| General Description of Recombinant Human Transcription factor SOX-2 Protein. | |
| Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in bryonic development such as YES1, FGF4, UTF1 and ZFP206 . Critical for early bryogenesis and for bryonic st cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural st cell self-renewal . Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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