PDF DatasheetHuman Hyaluronidase PH-20 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Hyaluronidase PH-20 based upon sequence from Human
Host: QP6719 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Hyaluronidase PH-20, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6719.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Leu36 – Ser490
Amino Acid Sequence: LNFRAPPVIP NVPFLWAWNA PSEFCLGKFD EPLDMSLFSF IGSPRINATG QGVTIFYVDR LGYYPYIDSI TGVTVNGGIP QKISLQDHLD KAKKDITFYM PVDNLGMAVI DWEEWRPTWA RNWKPKDVYK NRSIELVQQQ NVQLSLTEAT EKAKQEFEKA GKDFLVETIK LGKLLRPNHL WGYYLFPDCY NHHYKKPGYN GSCFNVEIKR NDDLSWLWNE STALYPSIYL NTQQSPVAAT LYVRNRVREA IRVSKIPDAK SPLPVFAYTR IVFTDQVLKF LSQDELVYTF GETVALGASG IVIWGTLSIM RSMKSCLLLD NYMETILNPY IINVTLAAKM CSQVLCQEQG VCIRKNWNSS DYLHLNPDNF AIQLEKGGKF TVRGKPTLED LEQFSEKFYC SCYSTLSCKE KADVKDTDAV DVCIADGVCI DAFLKPPMET EEPQIFYNAS PSTLS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Hyaluronidase PH-20 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Hyaluronidase PH-20 Protein General Information | |
|---|---|
| Alternate Names | |
| HEL-S-96n, HYAL1, SPAG15, HYAL5, PH20, HYA1, HYAL3, PH-20 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SPAM1 |
| Entrez Gene ID | 6677 |
| Ensemble Gene ID | ENSG00000106304 |
| RefSeq Protein Accession(s) | NP_001167515.1 |
| RefSeq mRNA Accession(s) | NM_001174044.1, NM_001174045.1, NM_001174046.1, NM_003117.4, NM_153189.2 |
| UniProt ID(s) | P38567 |
| UniGene ID(s) | Hs.121494 |
| HGNC ID(s) | HGNC:11217 |
| COSMIC ID Link(s) | SPAM1 |
| KEGG Gene ID(s) | hsa:6677 |
| PharmGKB ID(s) | PA36053 |
| General Description of Recombinant Human Hyaluronidase PH-20 Protein. | |
| Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are bedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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