PDF DatasheetHuman SPN / CD43 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant SPN / CD43 based upon sequence from Human
Host: QP6721 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) SPN / CD43, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6721.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Ser20 – Arg253
Amino Acid Sequence: STTAVQTPTS GEPLVSTSEP LSSKMYTTSI TSDPKADSTG DQTSALPPST SINEGSPLWT SIGASTGSPL PEPTTYQEVS IKMSSVPQET PHATSHPAVP ITANSLGSHT VTGGTITTNS PETSSRTSGA PVTTAASSLE TSRGTSGPPL TMATVSLETS KGTSGPPVTM ATDSLETSTG TTGPPVTMTT GSLEPSSGAS GPQVSSVKLS TMMSPTTSTN ASTVPFRNPD ENSR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human SPN / CD43 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human SPN / CD43 Protein General Information | |
|---|---|
| Alternate Names | |
| SPN, CD43, Ly-48, A630014B01Rik, Galgp, Cd43, Ly48 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SPN |
| Entrez Gene ID | 6693 |
| Ensemble Gene ID | ENSG00000197471 |
| RefSeq Protein Accession(s) | NP_001025459.1 |
| RefSeq mRNA Accession(s) | NM_001030288.2, NM_003123.4 |
| UniProt ID(s) | P16150 |
| UniGene ID(s) | Hs.632188 |
| HGNC ID(s) | HGNC:11249 |
| COSMIC ID Link(s) | SPN |
| KEGG Gene ID(s) | hsa:6693 |
| PharmGKB ID(s) | PA36079 |
| General Description of Recombinant Human SPN / CD43 Protein. | |
| One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 . During T-cell activation is actively roved from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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