PDF DatasheetMouse Sex-determining region Y protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Sex-determining region Y protein based upon sequence from Mouse
Host: QP6730 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Sex-determining region Y protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6730.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Gln144
Amino Acid Sequence: MEGHVKRPMN AFMVWSRGER HKLAQQNPSM QNTEISKQLG CRWKSLTEAE KRPFFQEAQR LKILHREKYP NYKYQPHRRA KVSQRSGILQ PAVASTKLYN LLQWDRNPHA ITYRQDWSRA AHLYSKNQQS FYWQPVDIPT GHLQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Sex-determining region Y protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Sex-determining region Y protein Protein General Information | |
|---|---|
| Alternate Names | |
| Tdy, Tdf | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Sry |
| Entrez Gene ID | 21674 |
| Ensemble Gene ID | ENSMUSG00000069036 |
| RefSeq Protein Accession(s) | NP_035694.1 |
| RefSeq mRNA Accession(s) | NM_011564.1 |
| UniProt ID(s) | Q05738 |
| UniGene ID(s) | Mm.377114 |
| COSMIC ID Link(s) | Sry |
| KEGG Gene ID(s) | mmu:21674 |
| General Description of Recombinant Mouse Sex-determining region Y protein Protein. | |
| Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons . Involved in different aspects of gene regulation including promoter activation or repression. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Promotes DNA bending. Also involved in pre-mRNA splicing . Binds to the DNA consensus sequence 5′-[AT]AACAA[AT]-3′.1 Publication | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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