PDF DatasheetHuman TANK Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant TANK based upon sequence from Human
Host: QP6760 protein expressed in E.coli, Yeast..
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TANK, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6760.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Arg119
Amino Acid Sequence: MDKNIGEQLN KAYEAFRQAC MDRDSAVKEL QQKTENYEQR IREQQEQLSL QQTIIDKLKS QLLLVNSTQD NNYGCVPLLE DSETRKNNLT LDQPQDKVIS GIAREKLPKV RRQEVSSPR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human TANK Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TANK Protein General Information | |
|---|---|
| Alternate Names | |
| TRAF2, I-TRAF, ITRAF, TRAF family member-associated NF-kappa-B activat | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TANK |
| Entrez Gene ID | 10010 |
| Ensemble Gene ID | ENSG00000136560 |
| RefSeq Protein Accession(s) | NP_001186064.1 |
| RefSeq mRNA Accession(s) | NM_001199135.1, NM_004180.2, NM_133484.1, XM_017003096.1, XM_017003097.1 |
| UniProt ID(s) | Q92844 |
| UniGene ID(s) | Hs.132257 |
| HGNC ID(s) | HGNC:11562 |
| COSMIC ID Link(s) | TANK |
| KEGG Gene ID(s) | hsa:10010 |
| PharmGKB ID(s) | PA36330 |
| General Description of Recombinant Human TANK Protein. | |
| Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining th in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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