PDF DatasheetHuman TIRAP Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant TIRAP based upon sequence from Human
Host: QP6797 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TIRAP, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6797.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MASSTSLPAP GSRPKKPLGK MADWFRQTLL KKPKKRPNSP ESTSSDASQP TSQDSPLPPS LSSVTSPSLP PTHASDSGSS RWSKDYDVCV CHSEEDLVAA QDLVSYLEGS TASLRCFLQL RDATPGGAIV SELCQALSSS HCRVLLITPG FLQDPWCKYQ MLQALTEAPG AEGCTIPLLS GLSRAAYPPE LRFMYYVDGR GPDGGFRQVK EAVMRYLQTL S
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human TIRAP Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TIRAP Protein General Information | |
|---|---|
| Alternate Names | |
| wyatt, BACTS1, MyD88-2, Mal, Toll/interleukin-1 receptor domain-containing adapter prote | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TIRAP |
| Entrez Gene ID | 114609 |
| Ensemble Gene ID | ENSG00000150455 |
| RefSeq Protein Accession(s) | NP_001034750.1 |
| RefSeq mRNA Accession(s) | NM_001039661.1, NM_001318776.1, NM_001318777.1, NM_148910.2, XM_005271399.3, XM_011542576.2, XM_017017162.1 |
| UniProt ID(s) | P58753 |
| UniGene ID(s) | Hs.537126 |
| HGNC ID(s) | HGNC:17192 |
| COSMIC ID Link(s) | TIRAP |
| KEGG Gene ID(s) | hsa:114609 |
| PharmGKB ID(s) | PA134972842 |
| General Description of Recombinant Human TIRAP Protein. | |
| Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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