Dog Tight junction protein ZO-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Tight junction protein ZO-1 based upon sequence from Dog
Host: QP6798 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Canis lupus familiaris (Dog) (Canis familiaris) Tight junction protein ZO-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6798.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Val1633 – Phe1769
Amino Acid Sequence: VVATARGVFN NNGGVLSSIE TGVSIIIPQG AIPEGVEQEI YFKVCRDNSI LPPLDKEKGE TLLSPLVMCG PHGLKFLKPV ELRLPHCASM TPDGWSFALK SSDSSSGDPK TWQNKCLPGD PNYLVGANCV SVLIDHF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Dog Tight junction protein ZO-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Canine Tight junction protein ZO-1 Protein General Information | |
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Alternate Names | |
ZO1, ZO-1 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | TJP1 |
Entrez Gene ID | 403752 |
RefSeq Protein Accession(s) | NP_001003140.1 |
RefSeq mRNA Accession(s) | NM_001003140.1 |
UniProt ID(s) | O97758 |
UniGene ID(s) | Cfa.3616 |
COSMIC ID Link(s) | TJP1 |
KEGG Gene ID(s) | cfa:403752 |
General Description of Recombinant Canine Tight junction protein ZO-1 Protein. | |
The N-terminal may be involved in transducing a signal required for tight junction assbly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells . |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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