PDF DatasheetMouse Toll-like receptor 7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Toll-like receptor 7 based upon sequence from Mouse
Host: QP6801 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Toll-like receptor 7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6801.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Phe27 – Ser348
Amino Acid Sequence: FRWFPKTLPC EVKVNIPEAH VIVDCTDKHL TEIPEGIPTN TTNLTLTINH IPSISPDSFR RLNHLEEIDL RCNCVPVLLG SKANVCTKRL QIRPGSFSGL SDLKALYLDG NQLLEIPQDL PSSLHLLSLE ANNIFSITKE NLTELVNIET LYLGQNCYYR NPCNVSYSIE KDAFLVMRNL KVLSLKDNNV TAVPTTLPPN LLELYLYNNI IKKIQENDFN NLNELQVLDL SGNCPRCYNV PYPCTPCENN SPLQIHDNAF NSLTELKVLR LHSNSLQHVP PTWFKNMRNL QELDLSQNYL AREIEEAKFL HFLPNLVELD FS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Mouse Toll-like receptor 7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse Toll-like receptor 7 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | Tlr7 |
| Entrez Gene ID | 170743 |
| Ensemble Gene ID | ENSMUSG00000044583 |
| RefSeq Protein Accession(s) | NP_001277684.1 |
| RefSeq mRNA Accession(s) | NM_001290755.1, NM_001290756.1, NM_001290757.1, NM_133211.4, XM_011247785.1, XM_011247786.1 |
| UniProt ID(s) | P58681 |
| UniGene ID(s) | Mm.23979 |
| COSMIC ID Link(s) | Tlr7 |
| KEGG Gene ID(s) | mmu:170743 |
| General Description of Recombinant Mouse Toll-like receptor 7 Protein. | |
| Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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