PDF DatasheetHuman TNFSF10 / TRAIL / APO-2L Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant TNFSF10 / TRAIL / APO-2L based upon sequence from Human
Host: QP6817 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TNFSF10 / TRAIL / APO-2L, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6817.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Thr39 – Gly281
Amino Acid Sequence: TNELKQMQDK YSKSGIACFL KEDDSYWDPN DEESMNSPCW QVKWQLRQLV RKMILRTSEE TISTVQEKQQ NISPLVRERG PQRVAAHITG TRGRSNTLSS PNSKNEKALG RKINSWESSR SGHSFLSNLH LRNGELVIHE KGFYYIYSQT YFRFQEEIKE NTKNDKQMVQ YIYKYTSYPD PILLMKSARN SCWSKDAEYG LYSIYQGGIF ELKENDRIFV SVTNEHLIDM DHEASFFGAF LVG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human TNFSF10 / TRAIL / APO-2L Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human TNFSF10 / TRAIL / APO-2L Protein General Information | |
|---|---|
| Alternate Names | |
| TNFSF10, TRAIL, APO-2L, Tnlg6a, Trail, TL2, Ly81, AI448571, APO-2L, A330042I21Rik | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFSF10 |
| Entrez Gene ID | 8743 |
| Ensemble Gene ID | ENSG00000121858 |
| RefSeq Protein Accession(s) | NP_001177871.1 |
| RefSeq mRNA Accession(s) | NM_001190942.1, NM_003810.3 |
| UniProt ID(s) | P50591 |
| UniGene ID(s) | Hs.478275 |
| HGNC ID(s) | HGNC:11925 |
| COSMIC ID Link(s) | TNFSF10 |
| KEGG Gene ID(s) | hsa:8743 |
| PharmGKB ID(s) | PA36618 |
| General Description of Recombinant Human TNFSF10 / TRAIL / APO-2L Protein. | |
| Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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