PDF DatasheetHuman Alpha-tocopherol transfer protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Alpha-tocopherol transfer protein based upon sequence from Human
Host: QP6847 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Alpha-tocopherol transfer protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6847.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Gln278
Amino Acid Sequence: MAEARSQPSA GPQLNALPDH SPLLQPGLAA LRRRAREAGV PLAPLPLTDS FLLRFLRARD FDLDLAWRLL KNYYKWRAEC PEISADLHPR SIIGLLKAGY HGVLRSRDPT GSKVLIYRIA HWDPKVFTAY DVFRVSLITS ELIVQEVETQ RNGIKAIFDL EGWQFSHAFQ ITPSVAKKIA AVLTDSFPLK VRGIHLINEP VIFHAVFSMI KPFLTEKIKE RIHMHGNNYK QSLLQHFPDI LPLEYGGEEF SMEDICQEWT NFIMKSEDYL SSISESIQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Alpha-tocopherol transfer protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Alpha-tocopherol transfer protein Protein General Information | |
|---|---|
| Alternate Names | |
| AVED, TTP1, alphaTTP, ATTP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TTPA |
| Entrez Gene ID | 7274 |
| Ensemble Gene ID | ENSG00000137561 |
| RefSeq Protein Accession(s) | NP_000361.1 |
| RefSeq mRNA Accession(s) | NM_000370.3 |
| UniProt ID(s) | P49638 |
| UniGene ID(s) | Hs.69049 |
| HGNC ID(s) | HGNC:12404 |
| COSMIC ID Link(s) | TTPA |
| KEGG Gene ID(s) | hsa:7274 |
| PharmGKB ID(s) | PA37068 |
| General Description of Recombinant Human Alpha-tocopherol transfer protein Protein. | |
| Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells (PubMed:7887897). Binds both phosphatidylinol 3,4-bisphosphate and phosphatidylinol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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