PDF DatasheetHuman Splicing factor U2AF 35 kDa subunit Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Splicing factor U2AF 35 kDa subunit based upon sequence from Human
Host: QP6861 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Splicing factor U2AF 35 kDa subunit, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6861.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Phe240
Amino Acid Sequence: MAEYLASIFG TEKDKVNCSF YFKIGACRHG DRCSRLHNKP TFSQTIALLN IYRNPQNSSQ SADGLRCAVS DVEMQEHYDE FFEEVFTEME EKYGEVEEMN VCDNLGDHLV GNVYVKFRRE EDAEKAVIDL NNRWFNGQPI HAELSPVTDF REACCRQYEM GECTRGGFCN FMHLKPISRE LRRELYGRRR KKHRSRSRSR ERRSRSRDRG RGGGGGGGGG GGGRERDRRR SRDRERSGRF
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Splicing factor U2AF 35 kDa subunit Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Splicing factor U2AF 35 kDa subunit Protein General Information | |
|---|---|
| Alternate Names | |
| RNU2AF1, FP793, RN, U2AFBP, U2AF35 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | U2AF1 |
| Entrez Gene ID | 102724594 |
| Ensemble Gene ID | ENSG00000160201 |
| RefSeq Protein Accession(s) | NP_001020374.1 |
| RefSeq mRNA Accession(s) | NM_001025203.1, NM_001025204.1, NM_001320646.1, NM_001320648.1, NM_001320651.1, NM_006758.2 |
| UniProt ID(s) | Q01081 |
| UniGene ID(s) | Hs.365116 |
| HGNC ID(s) | HGNC:12453 |
| COSMIC ID Link(s) | U2AF1 |
| KEGG Gene ID(s) | hsa:102724594 |
| PharmGKB ID(s) | PA37103 |
| General Description of Recombinant Human Splicing factor U2AF 35 kDa subunit Protein. | |
| Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3′-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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