Human Ubiquitin-conjugating enzyme E2 variant 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ubiquitin-conjugating enzyme E2 variant 2 based upon sequence from Human
Host: QP6864 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Ubiquitin-conjugating enzyme E2 variant 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6864.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Asn145
Amino Acid Sequence: AVSTGVKVPR NFRLLEELEE GQKGVGDGTV SWGLEDDEDM TLTRWTGMII GPPRTNYENR IYSLKVECGP KYPEAPPSVR FVTKINMNGI NNSSGMVDAR SIPVLAKWQN SYSIKVVLQE LRRLMMSKEN MKLPQPPEGQ TYNN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Ubiquitin-conjugating enzyme E2 variant 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human Ubiquitin-conjugating enzyme E2 variant 2 Protein General Information | |
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Alternate Names | |
DDVit-1, DDVIT1, UEV2, EDAF-1, EDPF1, EDPF-1, MMS2, UEV-2 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | UBE2V2 |
Entrez Gene ID | 7336 |
Ensemble Gene ID | ENSG00000169139 |
RefSeq Protein Accession(s) | NP_003341.1 |
RefSeq mRNA Accession(s) | NM_003350.2 |
UniProt ID(s) | Q15819 |
UniGene ID(s) | Hs.491695 |
HGNC ID(s) | HGNC:12495 |
COSMIC ID Link(s) | UBE2V2 |
KEGG Gene ID(s) | hsa:7336 |
PharmGKB ID(s) | PA37143 |
General Description of Recombinant Human Ubiquitin-conjugating enzyme E2 variant 2 Protein. | |
Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through ‘Lys-63’. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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