PDF DatasheetHuman UCHL5 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant UCHL5 based upon sequence from Human
Isoform: Isoform 4
Host: QP6866 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) UCHL5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6866.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 4
Expression Region: Met1 – Lys326
Amino Acid Sequence: MTGNAGEWCL MESDPGVFTE LIKGFGCRGA QVEEIWSLEP ENFEKLKPVH GLIFLFKWQP GEEPAGSVVQ DSRLDTIFFA KQVINNACAT QAIVSVLLNC THQDVHLGET LSEFKEFSQS FDAAMKGLAL SNSDVIRQVH NSFARQQMFE FDTKTSAKEE DAFHFVSYVP VNGRLYELDG LREGPIDLGA CNQDDWISAV RPVIEKRIQK YSEGEIRFNL MAIVSDRKMI YEQKIAELQR QLAEEPMDTD QGNSMLSAIQ SEVAKNQMLI EEEVQKLKRY KIENIRRKHN YLPFIMELLK TLAEHQQLIP LVEKFEKHFE KTLLGK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human UCHL5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human UCHL5 Protein General Information | |
|---|---|
| Alternate Names | |
| UCH-L5, CGI-70, UCH37, INO80R, Ubiquitin carboxyl-terminal hydrolase isozyme | |
| Molecular Weight | |
| Isoform 4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | UCHL5 |
| Entrez Gene ID | 51377 |
| Ensemble Gene ID | ENSG00000116750 |
| RefSeq Protein Accession(s) | NP_001186190.1 |
| RefSeq mRNA Accession(s) | NM_001199261.1, NM_001199262.1, NM_001199263.1, NM_015984.3 |
| UniProt ID(s) | Q9Y5K5 |
| UniGene ID(s) | Hs.145469 |
| HGNC ID(s) | HGNC:19678 |
| COSMIC ID Link(s) | UCHL5 |
| KEGG Gene ID(s) | hsa:51377 |
| PharmGKB ID(s) | PA134916228 |
| General Description of Recombinant Human UCHL5 Protein. | |
| Protease that specifically cleaves ‘Lys-48’-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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