PDF DatasheetHuman Vesicle-associated membrane protein 7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Vesicle-associated membrane protein 7 based upon sequence from Human
Host: QP6876 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Vesicle-associated membrane protein 7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6876.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Ala2 – Asn186
Amino Acid Sequence: AILFAVVARG TTILAKHAWC GGNFLEVTEQ ILAKIPSENN KLTYSHGNYL FHYICQDRIV YLCITDDDFE RSRAFNFLNE IKKRFQTTYG SRAQTALPYA MNSEFSSVLA AQLKHHSENK GLDKVMETQA QVDELKGIMV RNIDLVAQRG ERLELLIDKT ENLVDSSVTF KTTSRNLARA MCMKN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Vesicle-associated membrane protein 7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Vesicle-associated membrane protein 7 Protein General Information | |
|---|---|
| Alternate Names | |
| SYBL1, TIVAMP, VAMP-7, TI-VAMP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | VAMP7 |
| Entrez Gene ID | 6845 |
| Ensemble Gene ID | ENSG00000124333 |
| RefSeq Protein Accession(s) | NP_001138621.1 |
| RefSeq mRNA Accession(s) | NM_001145149.2, NM_001185183.1, NM_005638.5 |
| UniProt ID(s) | P51809 |
| UniGene ID(s) | Hs.24167 |
| HGNC ID(s) | HGNC:11486 |
| COSMIC ID Link(s) | VAMP7 |
| KEGG Gene ID(s) | hsa:6845 |
| PharmGKB ID(s) | PA162408786 |
| General Description of Recombinant Human Vesicle-associated membrane protein 7 Protein. | |
| Involved in the targeting and/or fusion of transport vesicles to their target mbrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocytosis of late endocytic vesicles during phagosome formation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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