PDF DatasheetHuman CD106 / VCAM1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CD106 / VCAM1 based upon sequence from Human
Host: QP6877 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CD106 / VCAM1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6877.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Phe25 – Glu698
Amino Acid Sequence: FKIETTPESR YLAQIGDSVS LTCSTTGCES PFFSWRTQID SPLNGKVTNE GTTSTLTMNP VSFGNEHSYL CTATCESRKL EKGIQVEIYS FPKDPEIHLS GPLEAGKPIT VKCSVADVYP FDRLEIDLLK GDHLMKSQEF LEDADRKSLE TKSLEVTFTP VIEDIGKVLV CRAKLHIDEM DSVPTVRQAV KELQVYISPK NTVISVNPST KLQEGGSVTM TCSSEGLPAP EIFWSKKLDN GNLQHLSGNA TLTLIAMRME DSGIYVCEGV NLIGKNRKEV ELIVQEKPFT VEISPGPRIA AQIGDSVMLT CSVMGCESPS FSWRTQIDSP LSGKVRSEGT NSTLTLSPVS FENEHSYLCT VTCGHKKLEK GIQVELYSFP RDPEIEMSGG LVNGSSVTVS CKVPSVYPLD RLEIELLKGE TILENIEFLE DTDMKSLENK SLEMTFIPTI EDTGKALVCQ AKLHIDDMEF EPKQRQSTQT LYVNVAPRDT TVLVSPSSIL EEGSSVNMTC LSQGFPAPKI LWSRQLPNGE LQPLSENATL TLISTKMEDS GVYLCEGINQ AGRSRKEVEL IIQVTPKDIK LTAFPSESVK EGDTVIISCT CGNVPETWII LKKKAETGDT VLKSIDGAYT IRKAQLKDAG VYECESKNKV GSQLRSLTLD VQGRENNKDY FSPE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CD106 / VCAM1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CD106 / VCAM1 Protein General Information | |
|---|---|
| Alternate Names | |
| CD106, VCAM1, INCAM-100, CD106 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | VCAM1 |
| Entrez Gene ID | 7412 |
| Ensemble Gene ID | ENSG00000162692 |
| RefSeq Protein Accession(s) | NP_001069.1 |
| RefSeq mRNA Accession(s) | NM_001078.3, NM_001199834.1, NM_080682.2 |
| UniProt ID(s) | P19320 |
| UniGene ID(s) | Hs.109225 |
| HGNC ID(s) | HGNC:12663 |
| COSMIC ID Link(s) | VCAM1 |
| KEGG Gene ID(s) | hsa:7412 |
| PharmGKB ID(s) | PA37286 |
| General Description of Recombinant Human CD106 / VCAM1 Protein. | |
| Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte igration to sites of inflammation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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