PDF DatasheetHuman WD repeat-containing protein 5 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant WD repeat-containing protein 5 based upon sequence from Human
Host: QP6884 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) WD repeat-containing protein 5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6884.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 – Cys334
Amino Acid Sequence: ATEEKKPETE AARAQPTPSS SATQSKPTPV KPNYALKFTL AGHTKAVSSV KFSPNGEWLA SSSADKLIKI WGAYDGKFEK TISGHKLGIS DVAWSSDSNL LVSASDDKTL KIWDVSSGKC LKTLKGHSNY VFCCNFNPQS NLIVSGSFDE SVRIWDVKTG KCLKTLPAHS DPVSAVHFNR DGSLIVSSSY DGLCRIWDTA SGQCLKTLID DDNPPVSFVK FSPNGKYILA ATLDNTLKLW DYSKGKCLKT YTGHKNEKYC IFANFSVTGG KWIVSGSEDN LVYIWNLQTK EIVQKLQGHT DVVISTACHP TENIIASAAL ENDKTIKLWK SDC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human WD repeat-containing protein 5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human WD repeat-containing protein 5 Protein General Information | |
|---|---|
| Alternate Names | |
| CFAP89, SWD3, BIG-3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | WDR5 |
| Entrez Gene ID | 11091 |
| Ensemble Gene ID | ENSG00000196363 |
| RefSeq Protein Accession(s) | NP_060058.1 |
| RefSeq mRNA Accession(s) | NM_017588.2, NM_052821.3, XM_005272163.1 |
| UniProt ID(s) | P61964 |
| UniGene ID(s) | Hs.397638 |
| HGNC ID(s) | HGNC:12757 |
| COSMIC ID Link(s) | WDR5 |
| KEGG Gene ID(s) | hsa:11091 |
| PharmGKB ID(s) | PA37361 |
| General Description of Recombinant Human WD repeat-containing protein 5 Protein. | |
| Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at ‘Lys-4’. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ‘Lys-4’ of histone H3. H3 ‘Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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