PDF DatasheetHuman DDB1- and CUL4-associated factor 7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DDB1- and CUL4-associated factor 7 based upon sequence from Human
Host: QP6885 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) DDB1- and CUL4-associated factor 7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6885.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Val342
Amino Acid Sequence: MSLHGKRKEI YKYEAPWTVY AMNWSVRPDK RFRLALGSFV EEYNNKVQLV GLDEESSEFI CRNTFDHPYP TTKLMWIPDT KGVYPDLLAT SGDYLRVWRV GETETRLECL LNNNKNSDFC APLTSFDWNE VDPYLLGTSS IDTTCTIWGL ETGQVLGRVN LVSGHVKTQL IAHDKEVYDI AFSRAGGGRD MFASVGADGS VRMFDLRHLE HSTIIYEDPQ HHPLLRLCWN KQDPNYLATM AMDGMEVVIL DVRVPCTPVA RLNNHRACVN GIAWAPHSSC HICTAADDHQ ALIWDIQQMP RAIEDPILAY TAEGEINNVQ WASTQPDWIA ICYNNCLEIL RV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human DDB1- and CUL4-associated factor 7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human DDB1- and CUL4-associated factor 7 Protein General Information | |
|---|---|
| Alternate Names | |
| SWAN-1, WDR68, HAN11, AN11 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DCAF7 |
| Entrez Gene ID | 10238 |
| Ensemble Gene ID | ENSG00000136485 |
| RefSeq Protein Accession(s) | NP_005819.3 |
| RefSeq mRNA Accession(s) | NM_005828.4 |
| UniProt ID(s) | P61962 |
| UniGene ID(s) | Hs.410596 |
| HGNC ID(s) | HGNC:30915 |
| KEGG Gene ID(s) | hsa:10238 |
| PharmGKB ID(s) | PA165431770 |
| General Description of Recombinant Human DDB1- and CUL4-associated factor 7 Protein. | |
| Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches . Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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