PDF DatasheetHuman YEATS domain-containing protein 4 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant YEATS domain-containing protein 4 based upon sequence from Human
Host: QP6895 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) YEATS domain-containing protein 4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6895.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ile227
Amino Acid Sequence: MFKRMAEFGP DSGGRVKGVT IVKPIVYGNV ARYFGKKREE DGHTHQWTVY VKPYRNEDMS AYVKKIQFKL HESYGNPLRV VTKPPYEITE TGWGEFEIII KIFFIDPNER PVTLYHLLKL FQSDTNAMLG KKTVVSEFYD EMIFQDPTAM MQQLLTTSRQ LTLGAYKHET EFAELEVKTR EKLEAAKKKT SFEIAELKER LKASRETINC LKNEIRKLEE DDQAKDI
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human YEATS domain-containing protein 4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human YEATS domain-containing protein 4 Protein General Information | |
|---|---|
| Alternate Names | |
| NUBI-1, 4930573H17Rik, B230215M10Rik, GAS41, YAF9 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | YEATS4 |
| Entrez Gene ID | 8089 |
| Ensemble Gene ID | ENSG00000127337 |
| RefSeq Protein Accession(s) | NP_001287879.1 |
| RefSeq mRNA Accession(s) | NM_001300950.1, NM_006530.3 |
| UniProt ID(s) | O95619 |
| UniGene ID(s) | Hs.4029 |
| HGNC ID(s) | HGNC:24859 |
| COSMIC ID Link(s) | YEATS4 |
| KEGG Gene ID(s) | hsa:8089 |
| PharmGKB ID(s) | PA134992686 |
| General Description of Recombinant Human YEATS domain-containing protein 4 Protein. | |
| Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome – DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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