PDF DatasheetRABV Phosphoprotein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Phosphoprotein based upon sequence from: RABV
Host: QP6952 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Rabies virus (strain PM) (RABV) Phosphoprotein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6952.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Cys297
Amino Acid Sequence: MSKIFVNPSA IRAGLADLEM AEETVDLINR NIEDNQAHLQ GEPIEVDNLP EDMGRLHLDD GKSPNPGEMA KVGEGKYRED FQMDEGEDPS FLFQSYLENV GVQIVRQMRS GERFLKIWSQ TVEEIISYVA VNFPNPPGKS SEDKSTQTTG RELKKETTPT PSQRESQSSK ARMAAQTASG PPALEWSATN EKDDLSVEAE IAHQIAESFS KKYKFPSRSS GILLYNFEQL KMNLDDIVKE AKNVPGVTRL AHDGSKLPLR CVLGWVALAN SKKFQLLVES DKLSKIMQDD LNRYTSC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of RABV Phosphoprotein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant RABV Phosphoprotein Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | P |
| UniProt ID(s) | P69480 |
| General Description of Recombinant RABV Phosphoprotein Protein. | |
| Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA tplate and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.