PDF DatasheetRotavirus Rotavirus A Outer capsid glycoprotein VP7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Rotavirus A Outer capsid glycoprotein VP7 based upon sequence from: Rotavirus
Host: QP7021 protein expressed in E. coli.
Tag: His-B2M
Protein Construction: A DNA sequence encoding the Rotavirus A (strain Human/United Kingdom/ST3/1975 G4-P2A[6]-I1-R1-C1-M1-A1-N1-T1-E1-H1) (RV-A) (Rotavirus A (strain St. Thomas 3)) Rotavirus A Outer capsid glycoprotein VP7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7021.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gln51 – Val326
Amino Acid Sequence: QNYGINLPIT GSMDTAYANS TQDNNFLFST LCLYYPSEAP TQISDTEWKD TLSQLFLTKG WPTGSVYFNE YSNVLEFSID PKLYCDYNVV LIRFVSGEEL DISELADLIL NEWLCNPMDI TLYYYQQTGE ANKWISMGSS CTVKVCPLNT QTLGIGCQTT NTATFETVAD SEKLAIIDVV DSVNHKLNIT STTCTIRNCN KLGPRENVAI IQVGGSNILD ITADPTTSPQ TERMMRVNWK KWWQVFYTVV DYINQIVQVM SKRSRSLDSS SFYYRV
Purity: Greater than 85% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Rotavirus Rotavirus A Outer capsid glycoprotein VP7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Rotavirus Rotavirus A Outer capsid glycoprotein VP7 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| UniProt ID(s) | P10501 |
| General Description of Recombinant Rotavirus Rotavirus A Outer capsid glycoprotein VP7 Protein. | |
| Outer capsid protein involved in attachment and possibly entry into the host epithelial cell. It is subsequently lost, together with VP4, following virus entry into the host cell. The outer layer contains 780 copies of VP7, grouped as 260 trimers. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. In integrin-dependent strains, VP7 seems to essentially target the integrin heterodimers ITGAX/ITGB2 and ITGA5/ITGB3 at a postbinding stage, once the initial attachment by VP4 has been achieved (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.