PDF DatasheetEpstein-Barr Latent membrane protein 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Latent membrane protein 1 based upon sequence from: Epstein-Barr
Host: QP7024 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Epstein-Barr virus (strain Raji) (HHV-4) (Human herpesvirus 4) Latent membrane protein 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7024.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Tyr185 – Asp386
Amino Acid Sequence: YYHGQRHSDE HHHDDSLPHP QQATDDSSNQ SDSNSNEGRH LLLVSGAGDG PPLCSQNLGA PGGGPNNGPQ DPDNTDDNGP QDPDNTDDNG PHDPLPQDPD NTDDNGPQDP DNTDDNGPHD PLPHNPSDSA GNDGGPPQLT EEVENKGGDQ GPPLMTDGGG GHSHDSGHDG IDPHLPTLLL GTSGSGGDDD DPHGPVQLSY YD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Epstein-Barr Latent membrane protein 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Epstein-Barr Latent membrane protein 1 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LMP1 |
| UniProt ID(s) | P13198 |
| General Description of Recombinant Epstein-Barr Latent membrane protein 1 Protein. | |
| Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. It is a short-lived protein probably degraded by the proteasome . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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