PDF DatasheetC. botulinum Botulinum neurotoxin type C1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Botulinum neurotoxin type C1 based upon sequence from: C. botulinum
Host: QP7104 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Clostridium botulinum Botulinum neurotoxin type C1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7104.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Pro2 – Asn428
Amino Acid Sequence: PITINNFNYS DPVDNKNILY LDTHLNTLAN EPEKAFRITG NIWVIPDRFS RNSNPNLNKP PRVTSPKSGY YDPNYLSTDS DKDPFLKEII KLFKRINSRE IGEELIYRLS TDIPFPGNNN TPINTFDFDV DFNSVDVKTR QGNNWVKTGS INPSVIITGP RENIIDPETS TFKLTNNTFA AQEGFGALSI ISISPRFMLT YSNATNDVGE GRFSKSEFCM DPILILMHEL NHAMHNLYGI AIPNDQTISS VTSNIFYSQY NVKLEYAEIY AFGGPTIDLI PKSARKYFEE KALDYYRSIA KRLNSITTAN PSSFNKYIGE YKQKLIRKYR FVVESSGEVT VNRNKFVELY NELTQIFTEF NYAKIYNVQN RKIYLSNVYT PVTANILDDN VYDIQNGFNI PKSNLNVLFM GQNLSRNPAL RKVNPEN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of C. botulinum Botulinum neurotoxin type C1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant C. botulinum Botulinum neurotoxin type C1 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| UniProt ID(s) | P18640 |
| General Description of Recombinant C. botulinum Botulinum neurotoxin type C1 Protein. | |
| Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves syntaxin. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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