Mouse Murinoglobulin-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Murinoglobulin-1 based upon sequence from: Mouse
Host: QP7135 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Murinoglobulin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7135.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Thr700 – Glu910
Amino Acid Sequence: TPEISWSLRT TLSKRPEEPP RKDPSSNDPL TETIRKYFPE TWVWDIVTVN STGLAEVEMT VPDTITEWKA GALCLSNDTG LGLSSVVPLQ AFKPFFVEVS LPYSVVRGEA FMLKATVMNY LPTSMQMSVQ LEASPDFTAV PVGDDQDSYC LSANGRHTSS WLVTPKSLGN VNFSVSAEAQ QSSEPCGSEV ATVPETGRKD TVVKVLIVEP E
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse Murinoglobulin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Mouse Murinoglobulin-1 Protein General Information | |
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Curated Database and Bioinformatic Data | |
Gene Symbol | Mug1 |
Entrez Gene ID | 17836 |
Ensemble Gene ID | ENSMUSG00000059908 |
RefSeq Protein Accession(s) | NP_032671.2 |
RefSeq mRNA Accession(s) | NM_008645.3 |
UniProt ID(s) | P28665 |
UniGene ID(s) | Mm.1311 |
KEGG Gene ID(s) | mmu:17836 |
General Description of Recombinant Mouse Murinoglobulin-1 Protein. | |
A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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