PDF DatasheetH. pylori DNA protection during starvation protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DNA protection during starvation protein based upon sequence from H. pylori
Host: QP7186 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) DNA protection during starvation protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7186.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ala144
Amino Acid Sequence: MKTFEILKHL QADAIVLFMK VHNFHWNVKG TDFFNVHKAT EEIYEEFADM FDDLAERIVQ LGHHPLVTLS EAIKLTRVKE ETKTSFHSKD IFKEILEDYK YLEKEFKELS NTAEKEGDKV TVTYADDQLA KLQKSIWMLQ AHLA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of H. pylori DNA protection during starvation protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant H. pylori DNA protection during starvation protein Protein General Information | |
|---|---|
| Alternate Names | |
| HP0243 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | dps |
| Entrez Gene ID | 898765 |
| RefSeq Protein Accession(s) | NP_207041.1 |
| RefSeq mRNA Accession(s) | NC_000915.1, NC_018939.1 |
| UniProt ID(s) | P43313 |
| KEGG Gene ID(s) | heo:C694_01230 |
| General Description of Recombinant H. pylori DNA protection during starvation protein Protein. | |
| Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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