PDF DatasheetC. botulinum Botulinum neurotoxin type F Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Botulinum neurotoxin type F based upon sequence from C. botulinum
Host: QP7209 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Clostridium botulinum Botulinum neurotoxin type F, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7209.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys436
Amino Acid Sequence: MPVAINSFNY NDPVNDDTIL YMQIPYEEKS KKYYKAFEIM RNVWIIPERN TIGTNPSDFD PPASLKNGSS AYYDPNYLTT DAEKDRYLKT TIKLFKRINS NPAGKVLLQE ISYAKPYLGN DHTPIDEFSP VTRTTSVNIK LSTNVESSML LNLLVLGAGP DIFESCCYPV RKLIDPDVVY DPSNYGFGSI NIVTFSPEYE YTFNDISGGH NSSTESFIAD PAISLAHELI HALHGLYGAR GVTYEETIEV KQAPLMIAEK PIRLEEFLTF GGQDLNIITS AMKEKIYNNL LANYEKIATR LSEVNSAPPE YDINEYKDYF QWKYGLDKNA DGSYTVNENK FNEIYKKLYS FTESDLANKF KVKCRNTYFI KYEFLKVPNL LDDDIYTVSE GFNIGNLAVN NRGQSIKLNP KIIDSIPDKG LVEKIVKFCK SVIPRK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of C. botulinum Botulinum neurotoxin type F Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant C. botulinum Botulinum neurotoxin type F Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | botF |
| UniProt ID(s) | P30996 |
| General Description of Recombinant C. botulinum Botulinum neurotoxin type F Protein. | |
| Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the ’58-Gln-|-Lys-59′ bond of synaptobrevins-1 and -2. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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