PDF DatasheetS. cerevisiae Nicotinamidase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Nicotinamidase based upon sequence from: S. cerevisiae
Host: QP7235 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker’s yeast) Nicotinamidase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7235.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Lys216
Amino Acid Sequence: MKTLIVVDMQ NDFISPLGSL TVPKGEELIN PISDLMQDAD RDWHRIVVTR DWHPSRHISF AKNHKDKEPY STYTYHSPRP GDDSTQEGIL WPVHCVKNTW GSQLVDQIMD QVVTKHIKIV DKGFLTDREY YSAFHDIWNF HKTDMNKYLE KHHTDEVYIV GVALEYCVKA TAISAAELGY KTTVLLDYTR PISDDPEVIN KVKEELKAHN INVVDK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of S. cerevisiae Nicotinamidase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant S. cerevisiae Nicotinamidase Protein General Information | |
|---|---|
| Alternate Names | |
| YGL037C | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PNC1 |
| Entrez Gene ID | 852846 |
| RefSeq Protein Accession(s) | NP_011478.3 |
| RefSeq mRNA Accession(s) | NM_001180902.3 |
| UniProt ID(s) | P53184 |
| KEGG Gene ID(s) | sce:YGL037C |
| General Description of Recombinant S. cerevisiae Nicotinamidase Protein. | |
| Catalyzes the deamidation of nicotinamide, an early step in the NAD+ salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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