PDF DatasheetHuman GNAS- subunit alpha isoforms short Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant GNAS- subunit alpha isoforms short based upon sequence from: Human
Host: QP7257 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GNAS- subunit alpha isoforms short, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7257.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Leu394
Amino Acid Sequence: MGCLGNSKTE DQRNEEKAQR EANKKIEKQL QKDKQVYRAT HRLLLLGAGE SGKSTIVKQM RILHVNGFNG EGGEEDPQAA RSNSDGEKAT KVQDIKNNLK EAIETIVAAM SNLVPPVELA NPENQFRVDY ILSVMNVPDF DFPPEFYEHA KALWEDEGVR ACYERSNEYQ LIDCAQYFLD KIDVIKQADY VPSDQDLLRC RVLTSGIFET KFQVDKVNFH MFDVGGQRDE RRKWIQCFND VTAIIFVVAS SSYNMVIRED NQTNRLQEAL NLFKSIWNNR WLRTISVILF LNKQDLLAEK VLAGKSKIED YFPEFARYTT PEDATPEPGE DPRVTRAKYF IRDEFLRIST ASGDGRHYCY PHFTCAVDTE NIRRVFNDCR DIIQRMHLRQ YELL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GNAS- subunit alpha isoforms short Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human GNAS- subunit alpha isoforms short Protein General Information | |
|---|---|
| Alternate Names | |
| GNAS1; GSP; SgVI; AHO; GPSA; C20orf45; GSA; POH; NESP; SCG6; Guanine nucleotide-binding protein G(s) subunit alpha isoforms sho | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GNAS |
| Entrez Gene ID | 2778 |
| Ensemble Gene ID | ENSG00000087460 |
| RefSeq Protein Accession(s) | NP_000507.1 |
| RefSeq mRNA Accession(s) | NM_000516.5, NM_001077488.3, NM_001077489.3, NM_001077490.2, NM_001309840.1, NM_080425.3, NM_080426.3 |
| UniProt ID(s) | P63092 |
| UniGene ID(s) | Hs.125898 |
| HGNC ID(s) | HGNC:4392 |
| COSMIC ID Link(s) | GNAS |
| KEGG Gene ID(s) | hsa:2778 |
| PharmGKB ID(s) | PA175 |
| General Description of Recombinant Human GNAS- subunit alpha isoforms short Protein. | |
| Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs) . Signaling involves the activation of adenylyl cyclases, resulting in increased levels of the signaling molecule cAMP . GNAS functions downstream of several GPCRs, including beta-adrenergic receptors . Stimulates the Ras signaling pathway via RAPGEF2 . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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