PDF DatasheetS. cerevisiae GTP-binding protein YPT1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant GTP-binding protein YPT1 based upon sequence from: S. cerevisiae
Host: QP7341 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker’s yeast) GTP-binding protein YPT1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7341.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Cys206
Amino Acid Sequence: MNSEYDYLFK LLLIGNSGVG KSCLLLRFSD DTYTNDYIST IGVDFKIKTV ELDGKTVKLQ IWDTAGQERF RTITSSYYRG SHGIIIVYDV TDQESFNGVK MWLQEIDRYA TSTVLKLLVG NKCDLKDKRV VEYDVAKEFA DANKMPFLET SALDSTNVED AFLTMARQIK ESMSQQNLNE TTQKKEDKGN VNLKGQSLTN TGGGCC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of S. cerevisiae GTP-binding protein YPT1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant S. cerevisiae GTP-binding protein YPT1 Protein General Information | |
|---|---|
| Alternate Names | |
| YFL038C | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | YPT1 |
| Entrez Gene ID | 850505 |
| RefSeq Protein Accession(s) | NP_116615.1 |
| RefSeq mRNA Accession(s) | NM_001179928.1 |
| UniProt ID(s) | P01123 |
| KEGG Gene ID(s) | sce:YFL038C |
| General Description of Recombinant S. cerevisiae GTP-binding protein YPT1 Protein. | |
| The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. YPT1 regulates the trafficking of secretory vesicles from the endoplasmic reticulum (ER) to the Golgi. Vesicular transport depends on shuttling of YPT1 between membrane and cytosol by GDI1, probably by recycling it to its membrane of origin after a vesicle fusion event. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum. Also involved in the recycling of membrane proteins. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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