PDF DatasheetP. gingivalis Lys-gingipain Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Lys-gingipain based upon sequence from: P. gingivalis
Host: QP7438 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Porphyromonas gingivalis (strain ATCC 33277 / DSM 20709 / JCM 12257) Lys-gingipain, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7438.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asp229 – Met594
Amino Acid Sequence: DVYTDHGDLY NTPVRMLVVA GAKFKEALKP WLTWKAQKGF YLDVHYTDEA EVGTTNASIK AFIHKKYNDG LAASAAPVFL ALVGDTDVIS GEKGKKTKKV TDLYYSAVDG DYFPEMYTFR MSASSPEELT NIIDKVLMYE KATMPDKSYL EKALLIAGAD SYWNPKIGQQ TIKYAVQYYY NQDHGYTDVY SYPKAPYTGC YSHLNTGVGF ANYTAHGSET SWADPSLTAT QVKALTNKDK YFLAIGNCCV TAQFDYPQPC FGEVMTRVKE KGAYAYIGSS PNSYWGEDYY WSVGANAVFG VQPTFEGTSM GSYDATFLED SYNTVNSIMW AGNLAATHAG NIGNITHIGA HYYWEAYHVL GDGSVM
Purity: Greater than 82.5% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of P. gingivalis Lys-gingipain Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant P. gingivalis Lys-gingipain Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | kgp |
| Entrez Gene ID | 29256891 |
| RefSeq Protein Accession(s) | WP_012458488.1 |
| RefSeq mRNA Accession(s) | NC_010729.1 |
| UniProt ID(s) | B2RLK2 |
| KEGG Gene ID(s) | pgn:PGN_1728 |
| General Description of Recombinant P. gingivalis Lys-gingipain Protein. | |
| Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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