PDF DatasheetHuman Serine / arginine-rich splicing factor 10 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Serine / arginine-rich splicing factor 10 based upon sequence from: Human
Isoform: Isoform 3
Host: QP7486 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Serine/arginine-rich splicing factor 10, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7486.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 3
Expression Region: Met1 – Ile183
Amino Acid Sequence: MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP RGFAYVQFED VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE GRNVYSSSRY DDYDRYRRSR SRSYERRRSR SRSFDYNYRR SYSPRNSRPT GRPRRSRSHS DNDRPNCSWN TQYSSAYYTS RKI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Serine / arginine-rich splicing factor 10 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Serine / arginine-rich splicing factor 10 Protein General Information | |
|---|---|
| Alternate Names | |
| PPP1R149; SFRS13A; TASR2; SFRS13; TASR; TASR1; FUSIP1; FUSIP2; NSSR; SRp38; SRrp40 | |
| Molecular Weight | |
| Isoform 3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SRSF10 |
| Entrez Gene ID | 10772 |
| Ensemble Gene ID | ENSG00000188529 |
| RefSeq Protein Accession(s) | NP_001177934.1 |
| RefSeq mRNA Accession(s) | NM_001191005.2, NM_001191006.2, NM_001191007.2, NM_001191009.2, NM_006625.5, NM_054016.3 |
| UniProt ID(s) | O75494 |
| UniGene ID(s) | Hs.3530 |
| HGNC ID(s) | HGNC:16713 |
| COSMIC ID Link(s) | SRSF10 |
| KEGG Gene ID(s) | hsa:10772 |
| PharmGKB ID(s) | PA28427 |
| General Description of Recombinant Human Serine / arginine-rich splicing factor 10 Protein. | |
| Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Ses to interfere with the U1 snRNP 5′-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. May be involved in regulation of alternative splicing in neurons, with isoform 1 acting as a positive and isoform 3 as a negative regulator. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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