PDF DatasheetHuman ZW10 interactor Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant ZW10 interactor based upon sequence from: Human
Host: QP7493 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) ZW10 interactor, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7493.
Bioactivity Data: Untested
Full Length? Full Length of BC020979
Expression Region: Met1 – Pro277
Amino Acid Sequence: MEAAETEAEA AALEVLAEVA GILEPVGLQE EAELPAKILV EFVVDSQKKD KLLCSQLQVA DFLQNILAQE DTAKGLDPLA SEDTSRQKAI AAKEQWKELK ATYREHVEAI KIGLTKALTQ MEEAQRKRTQ LREAFEQLQA KKQMAMEKRR AVQNQWQLQQ EKHLQHLAEV SAEVRERKTG TQQELDGVFQ KLGNLKQQAE QERDKLQRYQ TFLQLLYTLQ GKLLFPEAEA EAENLPDDKP QQPTRPQEQS TGDTMGRDPG VSFKAVGLQP AGDVNLP
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human ZW10 interactor Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human ZW10 interactor Protein General Information | |
|---|---|
| Alternate Names | |
| ZWINT1; HZwint-1; KNTC2AP; SIP30 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ZWINT |
| Entrez Gene ID | 11130 |
| Ensemble Gene ID | ENSG00000122952 |
| RefSeq Protein Accession(s) | NP_001005413.1 |
| RefSeq mRNA Accession(s) | NM_001005413.1, NM_007057.3, NM_032997.2 |
| UniProt ID(s) | O95229 |
| UniGene ID(s) | Hs.591363 |
| HGNC ID(s) | HGNC:13195 |
| COSMIC ID Link(s) | ZWINT |
| KEGG Gene ID(s) | hsa:11130 |
| PharmGKB ID(s) | PA37761 |
| General Description of Recombinant Human ZW10 interactor Protein. | |
| Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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