PDF DatasheetE. coli DNA mismatch repair protein MutL Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant DNA mismatch repair protein MutL based upon sequence from: E. coli
Host: QP7511 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Escherichia coli (strain K12) DNA mismatch repair protein MutL, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7511.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Glu615
Amino Acid Sequence: MPIQVLPPQL ANQIAAGEVV ERPASVVKEL VENSLDAGAT RIDIDIERGG AKLIRIRDNG CGIKKDELAL ALARHATSKI ASLDDLEAII SLGFRGEALA SISSVSRLTL TSRTAEQQEA WQAYAEGRDM NVTVKPAAHP VGTTLEVLDL FYNTPARRKF LRTEKTEFNH IDEIIRRIAL ARFDVTINLS HNGKIVRQYR AVPEGGQKER RLGAICGTAF LEQALAIEWQ HGDLTLRGWV ADPNHTTPAL AEIQYCYVNG RMMRDRLINH AIRQACEDKL GADQQPAFVL YLEIDPHQVD VNVHPAKHEV RFHQSRLVHD FIYQGVLSVL QQQLETPLPL DDEPQPAPRS IPENRVAAGR NHFAEPAARE PVAPRYTPAP ASGSRPAAPW PNAQPGYQKQ QGEVYRQLLQ TPAPMQKLKA PEPQEPALAA NSQSFGRVLT IVHSDCALLE RDGNISLLSL PVAERWLRQA QLTPGEAPVC AQPLLIPLRL KVSAEEKSAL EKAQSALAEL GIDFQSDAQH VTIRAVPLPL RQQNLQILIP ELIGYLAKQS VFEPGNIAQW IARNLMSEHA QWSMAQAITL LADVERLCPQ LVKTPPGGLL QSVDLHPAIK ALKDE
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of E. coli DNA mismatch repair protein MutL Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant E. coli DNA mismatch repair protein MutL Protein General Information | |
|---|---|
| Alternate Names | |
| ECK4166; JW4128; b4170 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | mutL |
| Entrez Gene ID | 948691 |
| RefSeq Protein Accession(s) | NP_418591.1 |
| RefSeq mRNA Accession(s) | NC_000913.3, NZ_LN832404.1 |
| UniProt ID(s) | P23367 |
| KEGG Gene ID(s) | ecj:JW4128 |
| General Description of Recombinant E. coli DNA mismatch repair protein MutL Protein. | |
| This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a “molecular matchmaker”, a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of the final effector complex. The ATPase activity of MutL is stimulated by DNA. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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