PDF DatasheetHuman ATP-dependent RNA helicase A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant ATP-dependent RNA helicase A based upon sequence from: Human
Host: QP7512 protein expressed in E.coli, Mammal..
Tag: His-Flag
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) ATP-dependent RNA helicase A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7512.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Asn325 – Asp840
Amino Acid Sequence: NQVGVVPWSP PQSNWNPWTS SNIDEGPLAF ATPEQISMDL KNELMYQLEQ DHDLQAILQE RELLPVKKFE SEILEAISQN SVVIIRGATG CGKTTQVPQF ILDDFIQNDR AAECNIVVTQ PRRISAVSVA ERVAFERGEE PGKSCGYSVR FESILPRPHA SIMFCTVGVL LRKLEAGIRG ISHVIVDEIH ERDINTDFLL VVLRDVVQAY PEVRIVLMSA TIDTSMFCEY FFNCPIIEVY GRTYPVQEYF LEDCIQMTHF VPPPKDKKKK DKDDDGGEDD DANCNLICGD EYGPETRLSM SQLNEKETPF ELIEALLKYI ETLNVPGAVL VFLPGWNLIY TMQKHLEMNP HFGSHRYQIL PLHSQIPREE QRKVFDPVPV GVTKVILSTN IAETSITIND VVYVIDSCKQ KVKLFTAHNN MTNYATVWAS KTNLEQRKGR AGRVRPGFCF HLCSRARFER LETHMTPEMF RTPLHEIALS IKLLRLGGIG QFLAKAIEPP PLDAVIEAEH TLRELD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human ATP-dependent RNA helicase A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human ATP-dependent RNA helicase A Protein General Information | |
|---|---|
| Alternate Names | |
| DDX9; LKP; NDH2; NDHII; RHA | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DHX9 |
| Entrez Gene ID | 1660 |
| Ensemble Gene ID | ENSG00000135829 |
| RefSeq Protein Accession(s) | NP_001348.2 |
| RefSeq mRNA Accession(s) | NM_001357.4 |
| UniProt ID(s) | Q08211 |
| UniGene ID(s) | Hs.191518 |
| HGNC ID(s) | HGNC:2750 |
| COSMIC ID Link(s) | DHX9 |
| KEGG Gene ID(s) | hsa:1660 |
| PharmGKB ID(s) | PA27232 |
| General Description of Recombinant Human ATP-dependent RNA helicase A Protein. | |
| Unwinds double-stranded DNA and RNA in a 3′ to 5′ direction. Alteration of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Component of the CRD-mediated complex that promotes MYC mRNA stability. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. As component of a large PER complex is involved in the inhibition of 3′ transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms. Positively regulates HIV-1 LTR-directed gene expression. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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