PDF DatasheetHuman Peptidyl-tRNA hydrolase ICT1, mitochondrial Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Peptidyl-tRNA hydrolase ICT1, mitochondrial based upon sequence from: Human
Host: QP7530 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Peptidyl-tRNA hydrolase ICT1, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7530.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Leu30 – Asp206
Amino Acid Sequence: LHKQKDGTEF KSIYSLDKLY PESQGSDTAW RVPNGAKQAD SDIPLDRLTI SYCRSSGPGG QNVNKVNSKA EVRFHLATAE WIAEPVRQKI AITHKNKINR LGELILTSES SRYQFRNLAD CLQKIRDMIT EASQTPKEPT KEDVKLHRIR IENMNRERLR QKRIHSAVKT SRRVDMD
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Peptidyl-tRNA hydrolase ICT1, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Peptidyl-tRNA hydrolase ICT1, mitochondrial Protein General Information | |
|---|---|
| Alternate Names | |
| DS1; ICT1; MRP-L58; DS-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ICT1 |
| Entrez Gene ID | 3396 |
| Ensemble Gene ID | ENSG00000167862 |
| RefSeq Protein Accession(s) | NP_001290194.1 |
| RefSeq mRNA Accession(s) | NM_001303265.1, NM_001545.2 |
| UniProt ID(s) | Q14197 |
| UniGene ID(s) | Hs.407955 |
| HGNC ID(s) | HGNC:5359 |
| COSMIC ID Link(s) | ICT1 |
| KEGG Gene ID(s) | hsa:3396 |
| PharmGKB ID(s) | PA29607 |
| General Description of Recombinant Human Peptidyl-tRNA hydrolase ICT1, mitochondrial Protein. | |
| Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been praturely terminated and thus in the recycling of stalled mitochondrial ribosomes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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