PDF DatasheetHuman Kynurenine–oxoglutarate transaminase 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Kynurenine–oxoglutarate transaminase 1 based upon sequence from: Human
Isoform: Isoform 2
Host: QP7538 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Kynurenine–oxoglutarate transaminase 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7538.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Leu372
Amino Acid Sequence: MAKQLQARRL DGIDYNPWVE FVKLASEHDV VNLGQGFPDF PPPDFAVEAF QHAVSGDFML NQYTKTFVII IEPFFDCYEP MTMMAGGRPV FVSLKPGPIQ NGELGSSSNW QLDPMELAGK FTSRTKALVL NTPNNPLGKV FSREELELVA SLCQQHDVVC ITDEVYQWMV YDGHQHISIA SLPGMWERTL TIGSAGKTFS ATGWKVGWVL GPDHIMKHLR TVHQNSVFHC PTQSQAAVAE SFEREQLLFR QPSSYFVQFP QAMQRCRDHM IRSLQSVGLK PIIPQGSYFL ITDISDFKRK MPDLPGAVDE PYDRRFVKWM IKNKGLVAIP VSIFYSVPHQ KHFDHYIRFC FVKDEATLQA MDEKLRKWKV EL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Kynurenine–oxoglutarate transaminase 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Kynurenine–oxoglutarate transaminase 1 Protein General Information | |
|---|---|
| Alternate Names | |
| CCBL1; KATI; GTK; KAT1 | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCBL1 |
| Entrez Gene ID | 883 |
| Ensemble Gene ID | ENSG00000171097 |
| RefSeq Protein Accession(s) | NP_001116143.1 |
| RefSeq mRNA Accession(s) | NM_001122671.1, NM_001122672.1, NM_004059.4, XM_011519168.1, XM_011519169.1, XM_011519170.2, XM_017015265.1, XM_017015266.1, XM_017015267.1, XM_017015268.1 |
| UniProt ID(s) | Q16773 |
| UniGene ID(s) | Hs.495250 |
| HGNC ID(s) | HGNC:1564 |
| COSMIC ID Link(s) | CCBL1 |
| KEGG Gene ID(s) | hsa:883 |
| PharmGKB ID(s) | PA26138 |
| General Description of Recombinant Human Kynurenine–oxoglutarate transaminase 1 Protein. | |
| Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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