PDF DatasheetHuman UDP-N-acetylhexosamine pyrophosphorylase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant UDP-N-acetylhexosamine pyrophosphorylase based upon sequence from: Human
Host: QP7555 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) UDP-N-acetylhexosamine pyrophosphorylase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7555.
Bioactivity Data: Untested
Full Length? Full Length of Isoform AGX1
Expression Region: Met1 – Ile505
Amino Acid Sequence: MNINDLKLTL SKAGQEHLLR FWNELEEAQQ VELYAELQAM NFEELNFFFQ KAIEGFNQSS HQKNVDARME PVPREVLGSA TRDQDQLQAW ESEGLFQISQ NKVAVLLLAG GQGTRLGVAY PKGMYDVGLP SRKTLFQIQA ERILKLQQVA EKYYGNKCII PWYIMTSGRT MESTKEFFTK HKYFGLKKEN VIFFQQGMLP AMSFDGKIIL EEKNKVSMAP DGNGGLYRAL AAQNIVEDME QRGIWSIHVY CVDNILVKVA DPRFIGFCIQ KGADCGAKVV EKTNPTEPVG VVCRVDGVYQ VVEYSEISLA TAQKRSSDGR LLFNAGNIAN HFFTVPFLRD VVNVYEPQLQ HHVAQKKIPY VDTQGQLIKP DKPNGIKMEK FVFDIFQFAK KFVVYEVLRE DEFSPLKNAD SQNGKDNPTT ARHALMSLHH CWVLNAGGHF IDENGSRLPA IPRLKDANDV PIQCEISPLI SYAGEGLESY VADKEFHAPL IIDENGVHEL VKNGI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human UDP-N-acetylhexosamine pyrophosphorylase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human UDP-N-acetylhexosamine pyrophosphorylase Protein General Information | |
|---|---|
| Alternate Names | |
| AGX2; SPAG2; AGX; AGX1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | UAP1 |
| Entrez Gene ID | 6675 |
| Ensemble Gene ID | ENSG00000117143 |
| RefSeq Protein Accession(s) | NP_001311042.1 |
| RefSeq mRNA Accession(s) | NM_001324113.1, NM_001324114.1, NM_001324115.1, NM_001324116.1, NM_001324117.1, NM_003115.4, XM_011509913.2, XM_011509914.2 |
| UniProt ID(s) | Q16222 |
| UniGene ID(s) | Hs.492859 |
| HGNC ID(s) | HGNC:12457 |
| COSMIC ID Link(s) | UAP1 |
| KEGG Gene ID(s) | hsa:6675 |
| PharmGKB ID(s) | PA37107 |
| General Description of Recombinant Human UDP-N-acetylhexosamine pyrophosphorylase Protein. | |
| Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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