PDF DatasheetHuman Dynactin subunit 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Dynactin subunit 1 based upon sequence from: Human
Host: QP7570 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Dynactin subunit 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7570.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Pro213 – Gln5
Amino Acid Sequence: PSKEEEGLRA QVRDLEEKLE TLRLKRAEDK AKLKELEKHK IQLEQVQEWK SKMQEQQADL QRRLKEARKE AKEALEAKER YMEEMADTAD AIEMATLDKE MAEERAESLQ QEVEALKERV DELTTDLEIL KAEIEEKGSD GAASSYQLKQ LEEQNARLKD ALVRMRDLSS SEKQEHVKLQ KLMEKKNQEL EVVRQQRERL QEELSQAEST IDELKEQVDA ALGAEEMVEM LTDRNLNLEE KVRELRETVG DLEAMNEMND ELQENARETE LELREQLDMA GARVREAQKR VEAAQETVAD YQQTIKKYRQ LTAHLQDVNR ELTNQQEASV ERQQQ
Purity: Greater than 84.6% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Dynactin subunit 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Dynactin subunit 1 Protein General Information | |
|---|---|
| Alternate Names | |
| P135; DAP-150; DP-150 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DCTN1 |
| Entrez Gene ID | 1639 |
| Ensemble Gene ID | ENSG00000204843 |
| RefSeq Protein Accession(s) | NP_001128512.1 |
| RefSeq mRNA Accession(s) | NM_001135040.2, NM_001135041.2, NM_001190836.1, NM_001190837.1, NM_004082.4, NM_023019.3 |
| UniProt ID(s) | Q14203 |
| UniGene ID(s) | Hs.516111 |
| HGNC ID(s) | HGNC:2711 |
| COSMIC ID Link(s) | DCTN1 |
| KEGG Gene ID(s) | hsa:1639 |
| PharmGKB ID(s) | PA27180 |
| General Description of Recombinant Human Dynactin subunit 1 Protein. | |
| Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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