PDF DatasheetHuman PD1 / PDCD1 / CD279 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant PD1 / PDCD1 / CD279 based upon sequence from: Human
Host: QP7574 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) PD1 / PDCD1 / CD279, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7574.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Pro21 – Val170
Amino Acid Sequence: PGWFLDSPDR PWNPPTFSPA LLVVTEGDNA TFTCSFSNTS ESFVLNWYRM SPSNQTDKLA AFPEDRSQPG QDCRFRVTQL PNGRDFHMSV VRARRNDSGT YLCGAISLAP KAQIKESLRA ELRVTERRAE VPTAHPSPSP RPAGQFQTLV
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human PD1 / PDCD1 / CD279 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human PD1 / PDCD1 / CD279 Protein General Information | |
|---|---|
| Alternate Names | |
| PD1; PDCD1; CD279; PD-1; CD279; hPD-l; hSLE1; SLEB2; PD1; hPD-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PDCD1 |
| Entrez Gene ID | 5133 |
| Ensemble Gene ID | ENSG00000188389 |
| RefSeq Protein Accession(s) | NP_005009.2 |
| RefSeq mRNA Accession(s) | NM_005018.2 |
| UniProt ID(s) | Q15116 |
| UniGene ID(s) | Hs.158297 |
| HGNC ID(s) | HGNC:8760 |
| COSMIC ID Link(s) | PDCD1 |
| KEGG Gene ID(s) | hsa:5133 |
| PharmGKB ID(s) | PA33110 |
| General Description of Recombinant Human PD1 / PDCD1 / CD279 Protein. | |
| Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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