Human POU domain class 2-associating factor 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant POU domain class 2-associating factor 1 based upon sequence from: Human
Host: QP7577 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) POU domain class 2-associating factor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7577.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Phe256
Amino Acid Sequence: MLWQKPTAPE QAPAPARPYQ GVRVKEPVKE LLRRKRGHAS SGAAPAPTAV VLPHQPLATY TTVGPSCLDM EGSVSAVTEE AALCAGWLSQ PTPATLQPLA PWTPYTEYVP HEAVSCPYSA DMYVQPVCPS YTVVGPSSVL TYASPPLITN VTTRSSATPA VGPPLEGPEH QAPLTYFPWP QPLSTLPTST LQYQPPAPAL PGPQFVQLPI SIPEPVLQDM EDPRRAASSL TIDKLLLEEE DSDAYALNHT LSVEGF
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human POU domain class 2-associating factor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
Recombinant Human POU domain class 2-associating factor 1 Protein General Information | |
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Alternate Names | |
OBF-1; OBF1; BOB1; OCAB | |
Curated Database and Bioinformatic Data | |
Gene Symbol | POU2AF1 |
Entrez Gene ID | 5450 |
Ensemble Gene ID | ENSG00000110777 |
RefSeq Protein Accession(s) | NP_006226.2 |
RefSeq mRNA Accession(s) | NM_006235.2 |
UniProt ID(s) | Q16633 |
UniGene ID(s) | Hs.654525 |
HGNC ID(s) | HGNC:9211 |
COSMIC ID Link(s) | POU2AF1 |
KEGG Gene ID(s) | hsa:5450 |
PharmGKB ID(s) | PA33535 |
General Description of Recombinant Human POU domain class 2-associating factor 1 Protein. | |
Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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