PDF DatasheetHuman Astrocytic phosphoprotein PEA-15 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Astrocytic phosphoprotein PEA-15 based upon sequence from: Human
Host: QP7581 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Astrocytic phosphoprotein PEA-15, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7581.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ala130
Amino Acid Sequence: MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEDELDTKLT RIPSAKKYKD IIRQPSEEEI IKLAPPPKKA
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Astrocytic phosphoprotein PEA-15 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Astrocytic phosphoprotein PEA-15 Protein General Information | |
|---|---|
| Alternate Names | |
| MAT1; PEA-15; HMAT1; MAT1H; HUMMAT1H; PED | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PEA15 |
| Entrez Gene ID | 8682 |
| Ensemble Gene ID | ENSG00000162734 |
| RefSeq Protein Accession(s) | NP_001284505.1 |
| RefSeq mRNA Accession(s) | NM_001297576.1, NM_001297577.1, NM_001297578.1, NM_003768.4, XM_006711599.2 |
| UniProt ID(s) | Q15121 |
| UniGene ID(s) | Hs.517216 |
| HGNC ID(s) | HGNC:8822 |
| COSMIC ID Link(s) | PEA15 |
| KEGG Gene ID(s) | hsa:8682 |
| PharmGKB ID(s) | PA33166 |
| General Description of Recombinant Human Astrocytic phosphoprotein PEA-15 Protein. | |
| Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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