PDF DatasheetHuman Transcription elongation factor A protein 2 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Transcription elongation factor A protein 2 based upon sequence from: Human
Host: QP7582 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Transcription elongation factor A protein 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7582.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Cys299
Amino Acid Sequence: MMGKEEEIAR IARRLDKMVT KKSAEGAMDL LRELKAMPIT LHLLQSTRVG MSVNALRKQS SDEEVIALAK SLIKSWKKLL DASDAKARER GRGMPLPTSS RDASEAPDPS RKRPELPRAP STPRITTFPP VPVTCDAVRN KCREMLTAAL QTDHDHVAIG ADCERLSAQI EECIFRDVGN TDMKYKNRVR SRISNLKDAK NPDLRRNVLC GAITPQQIAV MTSEEMASDE LKEIRKAMTK EAIREHQMAR TGGTQTDLFT CGKCRKKNCT YTQVQTRSSD EPMTTFVVCN ECGNRWKFC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Transcription elongation factor A protein 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Transcription elongation factor A protein 2 Protein General Information | |
|---|---|
| Alternate Names | |
| TFIIS | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TCEA2 |
| Entrez Gene ID | 6919 |
| Ensemble Gene ID | ENSG00000171703 |
| RefSeq Protein Accession(s) | NP_003186.1 |
| RefSeq mRNA Accession(s) | NM_003195.5, NM_198723.2, XM_017028036.1, XM_017028037.1 |
| UniProt ID(s) | Q15560 |
| UniGene ID(s) | Hs.505004 |
| HGNC ID(s) | HGNC:11614 |
| COSMIC ID Link(s) | TCEA2 |
| KEGG Gene ID(s) | hsa:6919 |
| PharmGKB ID(s) | PA36373 |
| General Description of Recombinant Human Transcription elongation factor A protein 2 Protein. | |
| Necessary for efficient RNA polymerase II transcription elongation past tplate-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3′-terminus. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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