PDF DatasheetHuman Histone-binding protein RBBP7 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Histone-binding protein RBBP7 based upon sequence from: Human
Host: QP7585 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Histone-binding protein RBBP7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7585.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Ser425
Amino Acid Sequence: MASKEMFEDT VEERVINEEY KIWKKNTPFL YDLVMTHALQ WPSLTVQWLP EVTKPEGKDY ALHWLVLGTH TSDEQNHLVV ARVHIPNDDA QFDASHCDSD KGEFGGFGSV TGKIECEIKI NHEGEVNRAR YMPQNPHIIA TKTPSSDVLV FDYTKHPAKP DPSGECNPDL RLRGHQKEGY GLSWNSNLSG HLLSASDDHT VCLWDINAGP KEGKIVDAKA IFTGHSAVVE DVAWHLLHES LFGSVADDQK LMIWDTRSNT TSKPSHLVDA HTAEVNCLSF NPYSEFILAT GSADKTVALW DLRNLKLKLH TFESHKDEIF QVHWSPHNET ILASSGTDRR LNVWDLSKIG EEQSAEDAED GPPELLFIHG GHTAKISDFS WNPNEPWVIC SVSEDNIMQI WQMAENIYND EESDVTTSEL EGQGS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Histone-binding protein RBBP7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Histone-binding protein RBBP7 Protein General Information | |
|---|---|
| Alternate Names | |
| RbAp46 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RBBP7 |
| Entrez Gene ID | 5931 |
| Ensemble Gene ID | ENSG00000102054 |
| RefSeq Protein Accession(s) | NP_001185648.1 |
| RefSeq mRNA Accession(s) | NM_001198719.1, NM_002893.3 |
| UniProt ID(s) | Q16576 |
| UniGene ID(s) | Hs.495755 |
| HGNC ID(s) | HGNC:9890 |
| COSMIC ID Link(s) | RBBP7 |
| KEGG Gene ID(s) | hsa:5931 |
| PharmGKB ID(s) | PA34254 |
| General Description of Recombinant Human Histone-binding protein RBBP7 Protein. | |
| Core histone-binding subunit that may target chromatin rodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assbly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome rodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome rodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome rodeling factor) complex. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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