PDF DatasheetHuman KYNU / Kynureninase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant KYNU / Kynureninase based upon sequence from: Human
Isoform: Isoform 2
Host: QP7587 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) KYNU / Kynureninase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7587.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Asn307
Amino Acid Sequence: MEPSSLELPA DTVQRIAAEL KCHPTDERVA LHLDEEDKLR HFRECFYIPK IQDLPPVDLS LVNKDENAIY FLGNSLGLQP KMVKTYLEEE LDKWAKIAAY GHEVGKRPWI TGDESIVGLM KDIVGANEKE IALMNALTVN LHLLMLSFFK PTPKRYKILL EAKAFPSDHY AIESQLQLHG LNIEESMRMI KPREGEETLR IEDILEVIEK EGDSIAVILF SGVHFYTGQH FNIPAITKAG QAKGCYVGFD LAHAVGNVEL YLHDWGVDFA CWCSYKYLNA GAGGIAGAFI HEKHAHTIKP ARSEFFN
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human KYNU / Kynureninase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human KYNU / Kynureninase Protein General Information | |
|---|---|
| Alternate Names | |
| KYNU; Kynureninase; 4432411A05Rik | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | KYNU |
| Entrez Gene ID | 8942 |
| Ensemble Gene ID | ENSG00000115919 |
| RefSeq Protein Accession(s) | NP_001028170.1 |
| RefSeq mRNA Accession(s) | NM_001032998.1, NM_001199241.1, NM_003937.2, XM_017005217.1 |
| UniProt ID(s) | Q16719 |
| UniGene ID(s) | Hs.470126 |
| HGNC ID(s) | HGNC:6469 |
| COSMIC ID Link(s) | KYNU |
| KEGG Gene ID(s) | hsa:8942 |
| PharmGKB ID(s) | PA30258 |
| General Description of Recombinant Human KYNU / Kynureninase Protein. | |
| Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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